The series was set around a general practice in north London and leading cast members included: Justine Lord, Nigel Stock, Barry Justice, Richard Leech, Isla Blair and Lynda La Plante (billed as Lynda Marchal). Nigel Stock's character, Dr. Thomas Owens, was the lead in a later spin-off series, Owen, M.D., which aired between 1971 and 1973. Most of the episodes produced are missing from the archives; 139 of the 160 shows are thought to be lost.
